Cov khoom
M-chlorodiphenylamine
Paub meej
Molecular Cov Qauv: C12h10Cln
Molecular Luj: 203.67
EINECS No.: 202-922-0
Lwm yam tshwj xeeb: organic chemistry; aratatics
Mol file: 101-17-7.mol
Melting taw tes: 112 ° C (ARV: Methanol (67-56-1))
Kub taw tes: 340 ° C
Qhov ceev: 1.21g / cm3
Cov ntsiab lus tsis pub: 1.6513 (kwv yees)
Kev Cia Siab Cia: 2-8 ° C
Solubility: Chloroform (me ntsis), MethChemicalbookanol (me ntsis)
Acidity Coefficient: (PKA) -0.20 ± 0.30 (kwv yees)
Daim ntawv: Roj
Xim: daj ntseg daj rau daj
CAS database: 101-17-7 (Casdatabase cuam tshuam)
Kev ua haujlwm lom neeg: 3-Chlorodiphenylamine yog ib qho kev sib raug zoo ntawm lub plawv Ca2 + sensitizer (Ca2 + sensitizer).3-Chlorodiphenylamine yog raws li cov qauv diphenylamine thiab tuaj yeem khi rau N-terminal domain ntawm cardiac troponin C (cTnC) (Kd = 6µM).3-chloriphenylamine, vim nws me me molecular loj, tuaj yeem ua qhov kev loj hlob ntawm lub zog CA2 + Sensitizing sib txuas rau kev kawm ntawm Systolic Plawv tsis ua haujlwm.
Target Kd: 6µM(N-domainofcardiactroponinC(cTnC))Kd:10µM(cNTnC–cSpchimera)
Tshuaj lom neeg cov khoom: kua.Boiling point: 335-336 ℃ (96.3kPa), txheeb ze ntom ntom 1.200, refractive index 1.6513.Soluble nyob rau hauv ethanol, benzene, acetic acid thiab ether.
Siv: m-chlorodiphenylamine yog cov organic intermediate ntawm diphenylamine, uas yog siv los ua cov tshuaj chlorpromrazine.
Cov txheej txheem ntau lawm: los ntawm kev sib xyaw ntawm o-chlorobenzoic acid thiab m-chloroaniline, thiab tom qab ntawd decarboxylated nrog hlau hmoov.
Cov Kev Nyab Xeeb Qeb Cai: 20/21/22
Cov Lus Qhia Kev Nyab Xeeb: 28-36 / 37
