Cov khoom
Retinoic acid
Cov qauv qauv
Qhov tshwm sim:Lub teeb txiv kab ntxwv los yog daj crystalline hmoov
Qhov ntom:1.0597 (zeeg)
Melting point:180-181 : kuv°C (lit.)
Boiling point:381.66 ib°C (kev kwv yees)
Refractivity:1.4800 (kwv yees)
Cov ntaub ntawv kev nyab xeeb
dav dav
Daim ntawv thov
Retinoic acid (tretinoin) yog vitamin A derivative.Nws tau pom tias muaj peev xwm hloov pauv collagen synthesis, nce dermal hyaluronic acid ntau ntau, thiab txhawb kev loj hlob ntawm fibroblast thiab extracellular matrix.Nws yog siv rau keratinization mob thiab kho pob txuv.
Vitamin A, nrog rau cov mis mos molecular C20H28O2, yog cov khoom lag luam nruab nrab ntawm cov vitamin A hauv lub cev, feem ntau cuam tshuam rau cov pob txha loj hlob thiab txhawb cov metabolic cuam tshuam ntawm epithelial cell proliferation, sib txawv thiab keratinolysis.Nws yog siv los kho pob txuv vulgaris, psoriasis, ichthyosis, lichen planus, plaub hau liab furunculosis, follicular keratosis, squamous cell carcinoma thiab melanoma.
Qeb: Cov tawv nqaij keratinization txawv txav, cell inducing differentiation agents
Cia tej yam kev mob: lub teeb-pov thawj thiab kaw
Retinoic acid tsis muaj kev cuam tshuam rau kev ua haujlwm tyrosinase thiab melanin muaj pes tsawg leeg ntawm tib neeg melanocytes.Thaum daim tawv nqaij raug kev laus ntawm lub cev los yog kev puas tsuaj los ntawm cov tshuaj, UV hluav taws xob lossis kev raug mob, retinoic acid kho lossis tiv thaiv qhov txawv txav ntawm cov tshuaj lom neeg muaj pes tsawg leeg thiab cov qauv morphological ntawm dermal connective cov ntaub so ntswg tshwm sim los ntawm cov teeb meem.Retinoic acid tsis muaj kev cuam tshuam rau cov tawv nqaij collagen synthesis.Tsis tas li ntawd, retinoic acid muaj ib qho kev tiv thaiv kev ua haujlwm ntawm leukocyte chemotaxis, yog li ua tus neeg sawv cev tiv thaiv kab mob.Retinoic acid tsis muaj kev cuam tshuam ncaj qha rau cov qog sebaceous thiab lawv qhov tso tawm.
